Article
Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases, and forensic implications.
American journal of human genetics - 10 Sept 2010
Ballantyne Kaye N, Goedbloed Miriam, Fang Rixun, Schaap Onno, Lao Oscar, Wollstein Andreas, Choi Ying, van Duijn Kate, Vermeulen Mark, Brauer Silke, Decorte Ronny, Poetsch Micaela, von Wurmb-Schwark Nicole, de Knijff Peter, Labuda Damian, Vézina Hélène, Knoblauch Hans, Lessig Rüdiger, Roewer Lutz, Ploski Rafal, Dobosz Tadeusz, Henke Lotte, Henke Jürgen, Furtado Manohar R, Kayser Manfred
Abstract excerpt
Nonrecombining Y-chromosomal microsatellites (Y-STRs) are widely used to infer population histories, discover genealogical relationships, and identify males for criminal justice purposes. Although a key requirement for their application is reliable mutability knowledge, empirical data are only available for a small number of Y-STRs thus far. To rectify this, we analyzed a large number of 186 Y-STR markers in...
Topics
- Chromosomes, Human, Y
- Forensic Sciences
- Genetic Loci
- Genetic Markers
- Humans
- Male
- Microsatellite Repeats
- Mutation
- Paternal Age