Article
Maximum likelihood estimation of locus-specific mutation rates in Y-chromosome short tandem repeats.
Bioinformatics (Oxford, England) - 15 Sept 2010
Ravid-Amir Osnat, Rosset Saharon
Abstract excerpt
MOTIVATION: Y-chromosome short tandem repeats (Y-STRs) are widely used for population studies, forensic purposes and, potentially, the study of disease, therefore knowledge of their mutation rate is valuable. Here we show a novel method for estimation of site-specific Y-STR mutation rates from partial phylogenetic information, via the maximum likelihood framework. RESULTS: Given Y-STR data classified into...
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