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Article

Population-Scale Sequencing Data Enable Precise Estimates of Y-STR Mutation Rates.

American journal of human genetics - 5 May 2016

Willems Thomas, Gymrek Melissa, Poznik G David, Tyler-Smith Chris, Erlich Yaniv

Abstract excerpt

Short tandem repeats (STRs) are mutation-prone loci that span nearly 1% of the human genome. Previous studies have estimated the mutation rates of highly polymorphic STRs by using capillary electrophoresis and pedigree-based designs. Although this work has provided insights into the mutational dynamics of highly mutable STRs, the mutation rates of most others remain unknown. Here, we harnessed whole-genome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27126583
DOI: 10.1016/j.ajhg.2016.04.001
PMCID: PMC4863667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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