Article

Cardiomyocyte mechanical memory is regulated through the talin interactome and DLC1 dependent regulation of RhoA

2023-07-19

Abstract excerpt

Mechanical properties are cues for many biological processes in health or disease. Likewise, in the heart it is becoming clearer that mechanical signals are critically involved in the disease progression. Cardiomyocytes sense the mechanical properties of their environment at costameres through integrins and associated proteins, including the mechanosensitive protein talin as an integral component. Our previous wor...

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Literature Corpus work: 9ecd9376-5396-51ce-8a10-03b8fe6fa067
DOI: 10.1101/2023.07.19.549635

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