Article

The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

2021-03-09

Abstract excerpt

Combinations of direct-acting antivirals are needed to minimize drug-resistance mutations and stably suppress replication of RNA viruses. Currently, there are limited therapeutic options against the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) and testing of a number of drug regimens has led to conflicting results. Here we show that cobicistat, which is an-FDA approved drug-booster that blocks the...

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Literature Corpus work: 9ec27f89-cae7-539c-a161-8e35f617af11
DOI: 10.1101/2021.03.09.434219

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