Article

Cancer-specific association between Tau ( <i>MAPT</i> ) and cellular pathways, clinical outcome, and drug response

2023-07-04

Abstract excerpt

Tau ( MAPT ) is a microtubule-associated protein causing common neurodegenerative diseases or inherited frontotemporal lobar degenerations. Emerging evidence for non-canonical functions of Tau in DNA repair and P53 regulation suggests its involvement in cancer. Indeed, preliminary studies have correlated Tau expression with cancer survival or response to therapies. To bring new evidence for a relevant role of Tau...

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Literature Corpus work: 9ec01b85-e10b-5066-bb42-a18d25c68946
DOI: 10.1101/2023.07.04.547660

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