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Epigenetic silencing of ferroptosis-regulating genes (PCBP1, GPX4, FTL) in cord blood: identification of novel biomarkers of fetal growth restriction induced by maternal smoking

2026-03-12

Abstract excerpt

<title>Abstract</title> <p>Maternal smoking is a leading preventable cause of intrauterine growth restriction (IUGR). While the clinical association is well-established, the molecular mechanisms linking prenatal smoke exposure and reduced fetal growth remain unclear. Ferroptosis, an iron-dependent form of cell death, has been implicated in placental pathology. This study aimed to validate epigenetic alterations i...

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Literature Corpus work
9e79bd54-b9a3-572e-a7e1-7676daffe451
DOI
10.21203/rs.3.rs-8918607/v1
Open publication

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Epigenetic silencing of ferroptosis-regulating genes (PCBP1, GPX4, FTL) in cord blood: identification of novel biomarkers of fetal growth restriction induced by maternal smokingDOI 10.21203/rs.3.rs-8918607/v1
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