Beyond Targeted Gene Panels: Whole-Exome Sequencing as a Strategic Platform for Precision Therapeutics in Alzheimer’s Disease

Abstract excerpt

Alzheimer’s disease (AD) continues to be one of the greatest challenges in public health due to its multifactorial and heterogeneous nature, involving multiple physiological axes that encompass a large number of genetic, metabolic, vascular, and inflammatory interactions. In current clinical practice, medical specialties, mainly neurology and psychiatry, still rely on targeted gene panels for genetic evaluation. A...

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• Amyotrophic Lateral Sclerosis Research
• Genetic Neurodegenerative Diseases
• Genomics and Rare Diseases

Identifiers and source

Literature Corpus work

9e6d65a8-ec76-5961-8529-556063a265be

DOI

10.3390/life16091410