Article

Levosimendan Ameliorates Adverse Pulmonary Vascular Remodeling in Group-2 Pulmonary Hypertension

2025-10-24

Abstract excerpt

<h4>Aims</h4> Pulmonary hypertension (PH) due to left heart disease (Group-2PH) is the most common form of PH and comprises two distinct subtypes: isolated post-capillary-PH (IpcPH) and combined post-and pre-capillary-PH (CpcPH). Despite its high prevalence and poor prognosis, no targeted therapies are currently approved, largely due to the absence of reliable preclinical models that recapitulate these human hemo...

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Literature Corpus work: 9e682220-b814-5a56-90fc-eca57a93d9fa
DOI: 10.1101/2025.10.23.684000

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