Article

High-Throughput Drug Screening on Borrelia Garinii and Borrelia Afzelii Identified Hypocrellin A as an Active Drug Candidate against Borrelia Species

2022-12-08

Abstract excerpt

Lyme disease (LD) is a tick-transmitted infection caused by Borrelia burgdorferi sensu lato species which includes B. burgdorferi, B. afzelii, and B. garinii. The majority of patients with early LD can be cured by standard treatment, yet some still suffer from post-treatment Lyme disease syndrome (PTLDS). The presence of Borrelia persisters has been proposed as a contributing factor, which cannnot be completely ki...

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Literature Corpus work: 9d92a592-91df-5ee1-ab12-2a3581b58b74
DOI: 10.20944/preprints202212.0140.v1

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