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A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity

2020-04-11

Abstract excerpt

<h4>ABSTRACT</h4> Advances in infectious disease control strategies through genetic manipulation of insect microbiomes have heightened interest in microbially produced small molecules within mosquitoes. Herein, 33 mosquito-associated bacterial genomes were mined and over 700 putative biosynthetic gene clusters (BGCs) were identified, 135 of which belong to known classes of BGCs. After an in-depth analysis of the...

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Literature Corpus work: c701d72c-a9a1-502f-ad43-3cc31e523f12
DOI: 10.1101/2020.04.09.034280

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