Article
The Central Importance of Hub Proteins in a Disease-Gene Network Model: A New Paradigm of Chronic Myeloid Leukemia Disease Study
2021-03-22
Abstract excerpt
<h4>Background</h4> The network biology of disease-gene association provides a holistic framework to decipher the intrinsic complexity of disease signaling pathways into cellular communication level. Different types of studies including large-scale genome-wide association, multifactor dimensional reduction analysis, whole genome, or exome-based sequencing strategies of diseases are striving to connect genes to di...
Topics
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- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Cytokine Signaling Pathways and Interactions
- Ferroptosis and cancer prognosis
- Histone Deacetylase Inhibitors Research
- Kruppel-like factors research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Identifiers and source
- Literature Corpus work
- 3ba6ffc9-e22b-5060-a201-a43ea3a2a9b9
- DOI
- 10.1101/2021.03.21.436331
