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Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia

18 Jan 2022

Abstract excerpt

BACKGROUND: Chronic myeloid leukemia (CML) is a malignant hyperplastic tumor of the bone marrow originating from pluripotent hematopoietic stem cells. The advent of tyrosine kinase inhibitors (TKIs) has greatly improved the survival rate of patients with CML. However, TKI-resistance leads to the disease recurrence and progression. This study aimed to identify immune-related genes (IRGs) associated with CML...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35111390
DOI: 10.7717/peerj.12616

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