Article

Evolution and adaptation of <i>Pseudomonas aeruginosa</i> in the paranasal sinuses of people with cystic fibrosis

2020-10-29

Abstract excerpt

People with the genetic disorder cystic fibrosis (CF) harbor lifelong respiratory infections, with morbidity and mortality frequently linked to chronic lung infections dominated by the opportunistically pathogenic bacterium Pseudomonas aeruginosa . During chronic CF lung infections, a single clone of P. aeruginosa can persist for decades and dominate end-stage CF lung disease due to its propensity to adaptively...

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Literature Corpus work: 9d45f81d-5fe4-54ee-b7cf-975ee1ed7b8f
DOI: 10.1101/2020.10.29.359844

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