Article

Gating effects of a Cav2.3 calcium channel mutation linked to developmental and epileptic encephalopathy

2026-05-26

Abstract excerpt

Developmental and epileptic encephalopathies (DEEs) are a group of neurological disorders primarily affecting young children and are characterized by severe seizures. DEEs are challenging to manage, with some patients experiencing severe side effects or not responding to frontline therapies. This is partly because of the many underlying mechanisms involved in DEE pathology and the relatively limited mechanism-spec...

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Literature Corpus work: 9d40b960-a76d-512f-a60f-ee187db71e10
DOI: 10.64898/2026.05.25.727692

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