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Article

Voltage-Gated Ion Channel Compensatory Effect in DEE: Implications for Future Therapies.

Cells - 24 Oct 2024

Shabani Khadijeh, Krupp Johannes, Lemesre Emilie, Lévy Nicolas, Tran Helene

Abstract excerpt

Developmental and Epileptic Encephalopathies (DEEs) represent a clinically and genetically heterogeneous group of rare and severe epilepsies. DEEs commonly begin early in infancy with frequent seizures of various types associated with intellectual disability and leading to a neurodevelopmental delay or regression. Disease-causing genomic variants have been identified in numerous genes and are implicated in over...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39513870
DOI: 10.3390/cells13211763
PMCID: PMC11544952

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