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Article

Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells

2020-09-09

Abstract excerpt

<h4>ABSTRACT</h4> Recombinant forms of the spike protein of SARS-CoV-2 and related viruses have proven difficult to produce with good yields in mammalian cells. Given the panoply of potential COVID-19 diagnostic tools and therapeutic candidates that require purified spike protein and its importance for ongoing SARS-CoV-2 research, we have explored new approaches for spike production and purification. Three transi...

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Literature Corpus work
9d2873b7-36a4-5a32-bbda-8e60727f954d
DOI
10.1101/2020.09.08.286732
Open publication

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Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cellsDOI 10.1101/2020.09.08.286732
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