Article

Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons

2024-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Rat post-mitotic septal neurons, engineered to proliferate and arrest under physiological conditions can be maintained for weeks without cytotoxic effects. Nine independent cDNA libraries were made to follow arrest-induced neural differentiation and innate immune responses in normal uninfected and CJ agent infected septal neurons for weeks. CJ infection created a non-productive latent (CJ-) and...

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Literature Corpus work: 9d07558c-66bf-5e11-8386-a6bf7811c118
DOI: 10.1101/2024.07.26.605349

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Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neuronsDOI 10.1101/2024.07.26.605349Read

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