Article

Physiological and Metabolomic Consequences of Reduced Expression of the Drosophila <i>brummer</i> Triglyceride Lipase

2021-08-04

Abstract excerpt

Disruption of lipolysis has widespread effects on intermediary metabolism and organismal phenotypes. Defects in lipolysis can be modeled in Drosophila melanogaster through genetic manipulations of brummer ( bmm ), which encodes a triglyceride lipase orthologous to mammalian Adipose Triglyceride Lipase. RNAi-mediated knock-down of bmm in all tissues or metabolic specific tissues results in reduced locomotor act...

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Literature Corpus work: 9ce5f33a-b157-51dd-8a63-6a5aed41a8b3
DOI: 10.1101/2021.08.04.455099

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