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A brain-specific microRNA, miR-1000, regulates lipid homeostasis via Neuropeptide-like precursor 1 in <i>Drosophila melanogaster</i>

2025-07-26

Abstract excerpt

Metabolism requires precise gene regulation to balance energy intake and expenditure for an organism’s well-being, with misregulation often leading to metabolic syndromes. This study reveals that the brain-specific microRNA miR-1000 regulates fat storage by controlling the expression of a neuropeptide gene, Nplp1 . Loss of miR-1000 increases Nplp1 expression, leading to higher body weight, increased fat storag...

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Identifiers and source

Literature Corpus work
404e4f60-5884-5197-af15-e56a0d81786a
DOI
10.1101/2025.07.22.666178
Open publication

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A brain-specific microRNA, miR-1000, regulates lipid homeostasis via Neuropeptide-like precursor 1 in <i>Drosophila melanogaster</i>DOI 10.1101/2025.07.22.666178
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