Article

Elevation of Gut-Derived p-Cresol During Spaceflight and its Effect on Drug Metabolism and Performance in Astronauts

2020-11-10

Abstract excerpt

Metabolites produced by enteric microbes may have important effects on astronauts on long-duration missions. The NASA Twins Study provided the most comprehensive multi-scale omics data to date from which to extract molecular features of potential clinical significance to spaceflight. From the multivariate data, we identified an elevation of the uremic toxin p -cresol, which is produced by gut microbial fermentati...

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Literature Corpus work: 9cdfaa82-b7c4-51e0-b343-22e51d6c2391
DOI: 10.1101/2020.11.10.374645

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