Article

Altered Fecal Microbiota and Urine Metabolome as Signatures of Soman Poisoning

2018-05-02

Abstract excerpt

The experimental pathophysiology of organophosphorus (OP) chemical exposure has been extensively reported. Here, we describe an altered fecal microbiota and urine metabolome that follows intoxication with soman, a lipophilic G class chemical warfare nerve agent. Non-anaesthetized Sprague-Dawley male rats were subcutaneously administered soman at 0.8 - 1.0 of the median lethal dose (LD 50 ) and evaluated for signs...

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Literature Corpus work: ea5cc16a-44b8-555f-9ad6-0f35f768451d
DOI: 10.1101/312660

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