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Concordance of claudin-18.2 expression in biopsy, resection, and recurrent specimens: implications for zolbetuximab therapy in pancreatic ductal adenocarcinoma

2025-04-18

Abstract excerpt

<h4>ABSTRACT</h4> Claudin-18.2 is a promising therapeutic target for gastrointestinal cancer. However, its expression pattern in pancreatic ductal adenocarcinoma, especially the concordance between biopsy and resection specimens, is unknown. This study aimed to evaluate the consistency of claudin-18.2 positivity across different specimen types using the clinically validated antibody clone 43-14A employed in ongoi...

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Literature Corpus work
9caaf9ac-39a7-54a7-bc2b-453bae8cdfa5
DOI
10.1101/2025.04.11.648482
Open publication

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Concordance of claudin-18.2 expression in biopsy, resection, and recurrent specimens: implications for zolbetuximab therapy in pancreatic ductal adenocarcinomaDOI 10.1101/2025.04.11.648482
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