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Article

Claudin-18.2 expression is frequent in remnant gastric carcinoma and associated with microsatellite instability and Epstein-Barr viral infection phenotypes.

Pathology - 1 Apr 2026

Chen Han-Ho, Liau Jau-Yu, Jeng Yung-Ming, Chen Kuo-Hsing, Tsai Jia-Huei

Abstract excerpt

Claudin-18.2 (CLDN18.2)-targeted therapeutics have been rapidly evolving. CLDN18.2 expression has not been evaluated in remnant gastric carcinoma. In this study, we analysed clinicopathological and molecular characteristics, including CLDN18.2 expression between remnant and conventional gastric carcinoma. Immunohistochemistry for CLDN18.2, p53, HER2, ARID1A, E-cadherin, CDX2, and mismatch repair proteins, as well...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41763978
DOI: 10.1016/j.pathol.2025.10.015

Genes

CLDN18
ARID1A
CDX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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