Article

Understanding the role of Pax5 in development of taxane-resistant neuroendocrine like prostate cancers

2023-12-11

Abstract excerpt

<title>Abstract</title> <p>Resistance to the current Androgen Receptor Signaling Inhibitor (ARSI) therapies has led to higher incidences of therapy-induced neuroendocrine-like prostate cancer (t-NEPC). This highly aggressive subtype with predominant small cell-like characteristics is resistant to taxane chemotherapies and has a dismal overall survival. t-NEPCs are mostly treated with platinum-based drugs with a c...

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Literature Corpus work: 9c91767f-dfce-5f3a-bd90-a8b4519b1d83
DOI: 10.21203/rs.3.rs-3464475/v1

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