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Article

Investigating causal relationships between exposome and human longevity: a Mendelian randomization analysis.

BMC medicine - 20 Jul 2021

Huang Shu-Yi, Yang Yu-Xiang, Chen Shi-Dong, Li Hong-Qi, Zhang Xue-Qing, Kuo Kevin, Tan Lan, Feng Lei, Dong Qiang, Zhang Can, Yu Jin-Tai

Abstract excerpt

BACKGROUND: Environmental factors are associated with human longevity, but their specificity and causality remain mostly unclear. By integrating the innovative "exposome" concept developed in the field of environmental epidemiology, this study aims to determine the components of exposome causally linked to longevity using Mendelian randomization (MR) approach. METHODS: A total of 4587 environmental exposures...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34281550
DOI: 10.1186/s12916-021-02030-4
PMCID: PMC8290559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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