Article

A pre-trained large generative model for translating single-cell transcriptome to proteome

2023-07-04

Abstract excerpt

Proteins are crucial for life, and measuring their abundance at the single-cell level can facilitate a high-resolution understanding of biological mechanisms in cellular processes and disease progression. However, current single-cell proteomic technologies face challenges such as limited coverage, throughput, and sensitivity, as well as batch effects, high costs, and stringent experimental operations. Drawing insp...

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Literature Corpus work: 9c893264-e1b2-5fbf-92b5-fad0380efc38
DOI: 10.1101/2023.07.04.547619

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