Article

Navitoclax mediates Interleukin-3 induced human umbilical vein endothelial cells survival and angiogenesis

2023-04-04

Abstract excerpt

Navitoclax is an effective pro-apoptotic agent against cancer cells. Uncontrolled cell survival is a hallmark of pathological angiogenesis in cancer and could promote plaque instability that contributes to atherosclerosis progression owing to intraplaque neovascularization. Cancer cell inhibition by navitoclax can restrain metastasis; therefore, it is possible to reduce endothelial cells survival and is expected t...

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Literature Corpus work: 9c41ea02-a574-5065-ab3a-74d295f94c54
DOI: 10.21203/rs.3.rs-2759691/v1

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