Article

Integrative metatranscriptomic analysis reveals disease-specific microbiome-host interactions in oral squamous cell carcinoma

2022-05-24

Abstract excerpt

<title>Abstract</title> Studies on the microbiome of oral squamous cell carcinoma (OSCC) have been largely limited to 16S rRNA gene sequencing. Here, we used laser microdissection coupled with metatranscriptome sequencing at unprecedented depth (~ 400 million sequences/sample) to simultaneously characterize the multi-kingdom microbiome and host transcriptomes and predict their interaction in OSCC. Analysis was...

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Literature Corpus work: 3f2d2446-4fe8-5592-bc89-9f151090820d
DOI: 10.21203/rs.3.rs-1689707/v1

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