Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Validation of an Automated, End-to-End Metagenomic Sequencing Assay for Agnostic Detection of Respiratory Viruses

2 May 2024

Abstract excerpt

BACKGROUND: Current molecular diagnostics are limited in the number and type of detectable pathogens. Metagenomic next-generation sequencing (mNGS) is an emerging, and increasingly feasible, pathogen-agnostic diagnostic approach. Translational barriers prohibit the widespread adoption of this technology in clinical laboratories. We validate an end-to-end mNGS assay for detection of respiratory viruses. Our assay...

Topics

Join the communities discussing this publication.

Genomics and Phylogenetic Studies
Respiratory viral infections research
SARS-CoV-2 detection and testing

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38696336
DOI: 10.1093/infdis/jiae226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Validation of an Automated, End-to-End Metagenomic Sequencing Assay for Agnostic Detection of Respiratory VirusesPMID 38696336Read ↗

Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discoverySemantic proximity Read ↗

Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discoverySemantic proximity Read ↗

Clinical validation of a novel metagenomic nanopore sequencing method for detecting viral respiratory pathogens: diagnostic accuracy studySemantic proximity Read ↗

Laboratory validation of a clinical metagenomic next-generation sequencing assay for respiratory virus detection and discoverySemantic proximity Read ↗

Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samplesSemantic proximity Read ↗

Nanopore Metagenomic Sequencing for Detection and Characterization of SARS-CoV-2 in Clinical SamplesSemantic proximity Read ↗

Comparative performance of three next-generation sequencing techniques in real clinical lower respiratory tract infectionsSemantic proximity Read ↗

Detection of respiratory viruses directly from clinical samples using next‐generation sequencing: A literature review of recent advances and potential for routine clinical useSemantic proximity Read ↗

Validation of an unbiased metagenomic detection assay for RNA viruses in viral transport media and plasmaSemantic proximity Read ↗

Quality control implementation for universal characterization of DNA and RNA viruses in clinical respiratory samples using single metagenomic next-generation sequencing workflowSemantic proximity Read ↗

Quality control implementation for universal characterization of DNA and RNA viruses in clinical respiratory samples using single metagenomic next-generation sequencing workflowSemantic proximity Read ↗

Retrospective Validation of a Metagenomic Sequencing Protocol for Combined Detection of RNA and DNA Viruses Using Respiratory Samples from Pediatric PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.