Article

N6-methyladenine DNA demethylase ALKBH1 regulates mammalian axon regeneration

2020-08-20

Abstract excerpt

Recent studies have shown that DNA N6-methyladenine (N6-mA) modification is emerging to be a novel and important epigenetic regulator of mammalian gene transcription. Several studies demonstrated DNA N6-mA in human or rodents was regulated by methyltransferase N6AMT1 and demethylase ALKBH1. Moreover, studies in mouse brain or human glioblastoma cells showed that reduced level of N6-mA or higher level of ALKBH1 was...

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Literature Corpus work: 9ba2460f-9d53-59ef-9f09-189e534a4f69
DOI: 10.1101/2020.08.19.258038

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