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Single-cell Sequencing-based Pre-implantation Genetic Testing-M (PGT-M) of the Heterozygous Mutations of PKD1 Gene

2020-12-02

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives: </bold>Polycystic kidney disease (PKD) is a common autosomal monogenic genetic disease. PKD1 mutation accounts for about 85% of ADPKD patients. Pre-implantation genetic testing-M (PGT-M for monogenic) is an important approach to prevent the transmission of genetic diseases from parents to the offspring. <bold>Design: </bold>In this study, We have identified the family...

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Literature Corpus work
9b456ac3-e9d9-5db5-9863-dcfacb56d728
DOI
10.21203/rs.3.rs-116726/v1
Open publication

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Single-cell Sequencing-based Pre-implantation Genetic Testing-M (PGT-M) of the Heterozygous Mutations of PKD1 GeneDOI 10.21203/rs.3.rs-116726/v1
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