Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The mutation-free embryo for in vitro fertilization selected by MALBAC-PGD resulted in a healthy live birth from a family carrying PKD 1 mutation.

Journal of assisted reproduction and genetics - 1 Dec 2017

Li Wen, Ma Yiyi, Yu Shengqiang, Sun Ningxia, Wang Liang, Chen Dongping, Yang Guijiang, Lu Sijia, Li Yangyang, Yang Bo, Mei Changlin

Abstract excerpt

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD, autosomal dominant PKD or adult-onset PKD) is the most prevalent and potentially lethal kidney disease that is hereditary and lacks effective treatment. Preimplantation genetic diagnosis (PGD) of embryos in assistant reproductive technology (ART) helps to select mutation-free embryos for blocking ADPKD inheritance from the parents to their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryo Transfer
Share to Fertilization in Vitro

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Live Birth

Share to Polycystic Kidney, Autosomal Dominant

Share to Pregnancy Outcome

Share to Preimplantation Diagnosis

Share to TRPP Cation Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 28825164
DOI: 10.1007/s10815-017-1018-z
PMCID: PMC5714816

Genes

PGD
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The mutation-free embryo for in vitro fertilization selected by MALBAC-PGD resulted in a healthy live birth from a family carrying PKD 1 mutation.PMID 28825164Read ↗

Single-cell Sequencing-based Pre-implantation Genetic Testing-M (PGT-M) of the Heterozygous Mutations of PKD1 GeneSemantic proximity Read ↗

A comprehensive PGT-M strategy for ADPKD patients with de novo PKD1 mutations using affected embryo or gametes as proband.Semantic proximity Read ↗

Blocker displacement amplification-based genetic diagnosis for autosomal dominant polycystic kidney disease and the clinical outcomes of preimplantation genetic testing.Semantic proximity Read ↗

Factors influencing the clinical outcome of preimplantation genetic testing for polycystic kidney diseaseSemantic proximity Read ↗

[Preimplantation genetic diagnosis for infertile males with autosomal dominant polycystic kidney disease].Semantic proximity Read ↗

Targeted long-read sequencing enables higher diagnostic yield of ADPKD by accurate PKD1 genetic analysis in an assisted reproductive centerSemantic proximity Read ↗

A long-read sequencing and SNP haplotype-based novel preimplantation genetic testing method for female ADPKD patient with de novo PKD1 mutationSemantic proximity Read ↗

Successful Combined Preimplantation Genetic Testing for Aneuploidy (PGT-A) and for Monogenic Disorders (PGT-M) for Autosomal Dominant Polycystic Kidney Disease Following Kidney Transplant: A Case ReportSemantic proximity Read ↗

A long-read sequencing and SNP haplotype-based novel preimplantation genetic testing method for female ADPKD patient with de novo PKD1 mutation.Semantic proximity Read ↗

Novel mutations of PKD genes in Chinese patients suffering from autosomal dominant polycystic kidney disease and seeking assisted reproductionSemantic proximity Read ↗

Combined Preimplantation Genetic Testing for Autosomal Dominant Polycystic Kidney Disease: Consequences for Embryos Available for TransferSemantic proximity Read ↗

Novel PGD strategy based on single sperm linkage analysis for carriers of single gene pathogenic variant and chromosome reciprocal translocation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.