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Article

Novel technologies emerging for preimplantation genetic diagnosis and preimplantation genetic testing for aneuploidy

18 Nov 2016

Abstract excerpt

INTRODUCTION: Preimplantation genetic diagnosis (PGD) was introduced as an alternative to prenatal diagnosis: embryos cultured in vitro were analysed for a monogenic disease and only disease-free embryos were transferred to the mother, to avoid the termination of pregnancy with an affected foetus. It soon transpired that human embryos show a great deal of acquired chromosomal abnormalities, thought to explain the...

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PMID: 27855520
DOI: 10.1080/14737159.2017.1262261

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