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Article

A novel monogenic preimplantation genetic testing strategy for sporadic polycystic kidney caused by de novo PKD1 mutation.

Clinical genetics - 1 Feb 2021

Shi Hao, Niu Wenbin, Liu Yidong, Jin Haixia, Song Wenyan, Shi Senlin, Yao Guidong, Xu Jiawei, Sun Yingpu

Abstract excerpt

Autosomal dominant hereditary polycystic kidney disease (ADPKD) is the most common inherited kidney disease that causes end-stage renal disease and kidney failure. Preimplantation genetic testing for monogenic (PGT-M) can effectively prevent the transmission of genetic diseases from parents to the offspring before pregnancy. However, PGT-M currently adopts the single nucleotide polymorphism (SNP) linkage analysis...

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Source

Identifiers

PMID: 33111320
DOI: 10.1111/cge.13871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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