Article

Computational Analysis of Silent Mutation Effects on SARS-CoV-2 RNA-Host RNA-Binding Protein Interactome

2025-10-03

Abstract excerpt

RNA-binding proteins (RBPs) play critical roles in host-virus interaction. They facilitate the regulation of viral RNA (vRNA) turnover by recognizing and forming complexes with the vRNA structure via specific RNA motifs-RNA binding domain interaction. However, due to consistent evolving nature of viruses, silent mutations in the viral genome can impact RBP-vRNA binding thereby altering the RNA processing. While ef...

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Literature Corpus work: 9a9cc41a-28eb-5bc6-96f7-3917bc928aeb
DOI: 10.1101/2025.09.22.677528

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