Article
Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants
2010-09-29
Abstract excerpt
About 80% of functional genes in the human genome are expressed in the brain and over 1,200 different genes have been associated with the pathogenesis of CNS disorders and dementia. Pharmacogenetic studies of psychotropic drug response have focused on determining the relationship between variations in specific candidate genes and the positive and adverse effects of drug treatment. Approximately, 18% of neuroleptic...
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Identifiers and source
- Literature Corpus work
- 9a7f8d18-9998-5a49-81f0-02f8beb00c3d
- DOI
- 10.3390/ph3103040