Back to search

Article

Identification of epigenetic silencing of the SFRP2 gene in Colorectal Cancer as a Clinical Biomarker and Molecular significance

2023-11-30

Abstract excerpt

<title>Abstract</title> <p>This study hypothesized that investigating the promoter methylation of SFRP2 gene in various biological samples from patients with CRC could offer novel biomarker utility. <h4>Methods:</h4> The study examined SFRP2 gene expression and methylation in both healthy individuals and CRC patients. We assessed the comprehensive biomarker description value of SFRP2 in CRC, validated SFRP2 expre...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9a488fde-1dec-5481-98ed-80469a300092
DOI
10.21203/rs.3.rs-3600319/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of epigenetic silencing of the SFRP2 gene in Colorectal Cancer as a Clinical Biomarker and Molecular significanceDOI 10.21203/rs.3.rs-3600319/v1
DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patientsSemantic proximity
Methylation of SFRP2 gene as a promising noninvasive biomarker using feces in colorectal cancer diagnosis: a systematic meta-analysisSemantic proximity
Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancerSemantic proximity
Hypermethylation of SFRP2 as a Potential Marker for Stool-Based Detection of Colorectal Cancer and Precancerous LesionsSemantic proximity
Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2 , and PRIMA1 in plasma samplesSemantic proximity
Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screeningSemantic proximity
A novel methylation site of SFRP1 Gene Promoter in colorectal cancer: Potential utility as biomarker for prognosis and immunotherapySemantic proximity
DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancerSemantic proximity
Methylation of the Polycomb Group Target Genes Is a Possible Biomarker for Favorable Prognosis in Colorectal CancerSemantic proximity
SFRP4 expression correlates with epithelial mesenchymal transition-linked genes and poor overall survival in colon cancer patientsSemantic proximity
Sensitive and Noninvasive Detection of Aberrant SFRP2 and MGMT-B Methylation in Iranian Patients with Colon Polyps.Semantic proximity
DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancerSemantic proximity
Select a neighboring publication to make it the new centre.