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Distinct Tumor-Associated Macrophage Signatures Shape the Immune Microenvironment and Patient Prognosis in Renal Cell Carcinoma

2025-05-07

Abstract excerpt

Renal cell carcinoma (RCC) accounts for 90% of adult renal cancer cases and is characterized by significant heterogeneity within its tumor microenvironment. This study tests the hypothesis that tumor-associated macrophages (TAMs) influence RCC progression and patient response to treatment by investigating the prognostic implications of TAM signatures. Utilizing independent single-cell RNA sequencing data from RCC...

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Literature Corpus work
99aeeb34-2edb-57df-8f9a-092901612083
DOI
10.20944/preprints202505.0341.v1
Open publication

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Distinct Tumor-Associated Macrophage Signatures Shape the Immune Microenvironment and Patient Prognosis in Renal Cell CarcinomaDOI 10.20944/preprints202505.0341.v1
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