Article
Identification of Novel Candidate Inhibitors Targeting hBCATm for Acute Liver Failure by In Silico Methods
2026-08-10
Abstract excerpt
<title>Abstract</title> <p> Acute liver failure (ALF) is a life-threatening disease characterized by severe metabolic dysregulation and limited treatment approaches. Human mitochondrial branched-chain aminotransferase (hBCATm), involved in branched-chain amino acid metabolism, plays a critical role as a key target in ALF treatment options. This study aimed to derivatize new molecules more effective against hBCAT...
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Identifiers and source
- Literature Corpus work
- 994f8b37-6f67-534a-af20-fcf6213f7dad
- DOI
- 10.21203/rs.3.rs-9987044/v1
