Article

Adeno-Associated Virus (AAV) Vectors in the CNS

2011-06-01

Abstract excerpt

Adeno-associated virus (AAV) vectors exhibit a number of properties that have made this vector system an excellent choice for both CNS gene therapy and basic neurobiological investigations. In vivo, the preponderance of AAV vector transduction occurs in neurons where it is possible to obtain long-term, stable gene expression with very little accompanying toxicity. Promoter selection, however, significantly influen...

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Identifiers and source

Literature Corpus work: 993a5e33-973e-5bc9-8ee7-f72144c0bb1d
DOI: 10.2174/156652311795684759

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