Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AAV-Mediated Gene Therapy for Research and Therapeutic Purposes

1 Oct 2014

Abstract excerpt

Adeno-associated virus (AAV) is a small, nonenveloped virus that was adapted 30 years ago for use as a gene transfer vehicle. It is capable of transducing a wide range of species and tissues in vivo with no evidence of toxicity, and it generates relatively mild innate and adaptive immune responses. We review the basic biology of AAV, the history of progress in AAV vector technology, and some of the clinical and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Interference and Gene Delivery
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26958729
DOI: 10.1146/annurev-virology-031413-085355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AAV-Mediated Gene Therapy for Research and Therapeutic PurposesPMID 26958729Read ↗

Adeno-Associated Virus (AAV) as a Vector for Gene TherapySemantic proximity Read ↗

Adeno-Associated Virus at 50: A Golden Anniversary of Discovery, Research, and Gene Therapy Success—A Personal PerspectiveSemantic proximity Read ↗

Rationale and strategies for the development of safe and effective optimized AAV vectors for human gene therapySemantic proximity Read ↗

Gene Therapy Using Adeno-Associated Virus VectorsSemantic proximity Read ↗

AAV-Based Gene Therapy: Opportunities, Risks, and Scale-Up StrategiesSemantic proximity Read ↗

Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research ApplicationsSemantic proximity Read ↗

AAV vector development, back to the futureSemantic proximity Read ↗

Biosafety of Recombinant Adeno-associated Virus VectorsSemantic proximity Read ↗

In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human diseaseSemantic proximity Read ↗

In vivo applications and toxicities of AAV-based gene therapies in rare diseasesSemantic proximity Read ↗

Revolution of AAV in Drug Discovery: From Delivery System to Clinical ApplicationSemantic proximity Read ↗

Adeno-Associated Virus Gene Therapy for Liver DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.