Article

Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 and golden Syrian hamster upon SARS-CoV-2 infection.

2023-05-05

Abstract excerpt

<title>Abstract</title> <p>Safe and effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have been crucial to fight against the coronavirus disease 2019 pandemic. Most vaccines are based on a mutated version of the Spike glycoprotein [K986P/V987P (S-2P)] with improved stability, yield and immunogenicity. However, S-2P is still produced at low levels. Here, we described a novel V987H mut...

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Literature Corpus work: 991d248a-0768-5e71-a702-19f823c96d2f
DOI: 10.21203/rs.3.rs-2846684/v1

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