Effects of polygenic liability for autism on neonatal thalamocortical connectivity and behavioral outcomes across sex

Abstract excerpt

Functional brain networks are altered in Autism Spectrum Disorder (ASD), with differences in thalamocortical connectivity detectable as early as infancy. ASD shows distinct sex differences, not only in diagnostic rates, but also in brain and behavioral manifestations of the condition. Although common variants account for much of the genetic liability for ASD, little is known about the impact of ASD-associated gene...

Topics

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• Autism Spectrum Disorder
• Cerebral Cortex
• Child Behavior Disorders
• Diffusion Tensor Imaging
• Genetic Predisposition to Disease
• Neural Pathways
• Psychomotor Performance
• Social Behavior

Identifiers and source

Literature Corpus work

9911eb71-54ce-529a-9c39-065a18d43783

DOI

10.64898/2025.12.23.25342934