Uncovering the Role of Biological Sex in the Divergent Genetic Profiles of Early and Late-Diagnosed Autism

Abstract excerpt

<title>Abstract</title> <p>Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a significant male prevalence bias. While recent evidence suggests that genetic heterogeneity is indexed by age at diagnosis, males are also typically diagnosed earlier, such that the extent to which these age-specific findings are confounded by shared genetic signal with sex-specific genetic architecture remains uncle...

Topics

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• Attention Deficit Disorder with Hyperactivity
• Autism Spectrum Disorder
• Child
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Latent Class Analysis
• Polymorphism, Single Nucleotide
• Transcriptome

Identifiers and source

Literature Corpus work

06378350-4678-5a6f-9a87-203ffacf7886

DOI

10.21203/rs.3.rs-9623041/v1