Article
A neurogenetic analysis of female autism.
Brain : a journal of neurology - 28 Jul 2021
Jack Allison, Sullivan Catherine A W, Aylward Elizabeth, Bookheimer Susan Y, Dapretto Mirella, Gaab Nadine, Van Horn John D, Eilbott Jeffrey, Jacokes Zachary, Torgerson Carinna M, Bernier Raphael A, Geschwind Daniel H, McPartland James C, Nelson Charles A, Webb Sara J, Pelphrey Kevin A, Gupta Abha R
Abstract excerpt
Females versus males are less frequently diagnosed with autism spectrum disorder (ASD), and while understanding sex differences is critical to delineating the systems biology of the condition, female ASD is understudied. We integrated functional MRI and genetic data in a sex-balanced sample of ASD and typically developing youth (8-17 years old) to characterize female-specific pathways of ASD risk. Our primary...
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