Article

Paternal Obesity and Epigenetic Inheritance of Breast Cancer: The Role of Systemic Effects and Transmission to the Second Generation

2020-12-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> While genetics explains some familial breast cancer cases, we showed that environmentally-induced epigenetic inheritance of breast cancer can also occur in rodent models. We previously reported that paternal consumption of a high-fat diet and ensuing obesity increased breast cancer susceptibility in the offspring (F1). Nevertheless, it is still unclear whether p...

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Literature Corpus work: 6b1f7229-388f-5882-8f9c-f8caaa5c3a36
DOI: 10.21203/rs.3.rs-118267/v1

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