Article

The human CD40 agonistic antibody ADC-1013 generates immune mediated anti-tumor effects in syngeneic tumor models in hCD40 transgenic mice

2014-01-01

Abstract excerpt

No abstract is available from the source.

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 98ed4c31-edc1-5475-81ff-4fe5e989b543
DOI: 10.1186/2051-1426-2-s3-p251
PMCID: PMC4292546

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The human CD40 agonistic antibody ADC-1013 generates immune mediated anti-tumor effects in syngeneic tumor models in hCD40 transgenic miceDOI 10.1186/2051-1426-2-s3-p251Read

Antibody discovery: the use of transgenic mice to generate human monoclonal antibodies for therapeuticsSemantic proximity Read

CSF-1R–Dependent Lethal Hepatotoxicity When Agonistic CD40 Antibody Is Given before but Not after ChemotherapySemantic proximity Read

Cell targeting and immunostimulatory properties of a novel Fcγ-receptor independent agonistic anti-CD40 antibody in rhesus macaquesSemantic proximity Read

A Nonhuman Primate Model for the Selective Elimination of CD8+ Lymphocytes Using a Mouse-Human Chimeric Monoclonal AntibodySemantic proximity Read

Agonistic anti-CD40 converts Tregs into Type 1 effectors within the tumor micro-environmentSemantic proximity Read

DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing.Semantic proximity Read

Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor ImmunitySemantic proximity Read

From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic miceSemantic proximity Read

Combined cytotoxic and immune-stimulatory gene therapy using Ad-TK and Ad-Flt3L: Translational developments from rodents to glioma patientsSemantic proximity Read

A human programmed death-ligand 1-expressing mouse tumor model for evaluating the therapeutic efficacy of anti-human PD-L1 antibodies.Semantic proximity Read

High-avidity human IgGκ monoclonal antibodies from a novel strain of minilocus transgenic miceSemantic proximity Read

Domain Binding and Isotype Dictate the Activity of Anti-human OX40 AntibodiesSemantic proximity Read