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Immunogenetic regulation of Natural Killer cell function in pregnancy

2017-01-01

Abstract excerpt

Uterine NK (uNK) cells are a distinct subset of NK cells in the decidua of humans and rodents during pregnancy, which are essential for remodelling of the spiral arteries supplying the feto-placental unit. Similarly to peripheral NK cells, uNK cells express Natural Killer receptors (NKRs) that engage MHC class I molecules. Evidence from human genetic association studies suggests that, in the presence of allogeneic...

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Literature Corpus work
98e71f77-f95c-582f-95a5-37c796d62ce2
DOI
10.17863/cam.17184
Open publication

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