Article
Role of Decidual Natural Killer Cells in Human Pregnancy and Related Pregnancy Complications.
Frontiers in immunology - 1 Jan 2021
Zhang Xiuhong, Wei Haiming
Abstract excerpt
Pregnancy is a unique type of immunological process. Healthy pregnancy is associated with a series of inflammatory events: implantation (inflammation), gestation (anti-inflammation), and parturition (inflammation). As the most abundant leukocytes during pregnancy, natural killer (NK) cells are recruited and activated by ovarian hormones and have pivotal roles throughout pregnancy. During the first trimester, NK...
Topics
- Animals
- Cytokines
- Cytotoxicity, Immunologic
- Decidua
- Embryo Implantation
- Female
- Fetal Development
- Histocompatibility, Maternal-Fetal
- Humans
- Immune Tolerance
- Killer Cells, Natural
- Parturition
- Phenotype
- Placentation
- Pregnancy
- Pregnancy Complications
- Signal Transduction
